Cough Science News
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
This month’s roundup explores placebo effects in RCC trials, the role of interoception in chronic cough, and the cost burden of persistent symptoms, plus insights from Dr. Nadia Giannetti.
New key cough science publications, Actigraph x Hyfe partnership and more
This year marked significant progress in cough monitoring, solidifying cough as a valuable biomarker in diverse therapeutic areas
New findings on refractory chronic cough (RCC), pulmonary tuberculosis, and pulmonary fibrosis. Plus latest white papers by Hyfe.
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News, August 2024 - Explore studies on cough variability, acute cough duration, and the cost burden of chronic cough. Plus, discover the world’s most comprehensive collection of cinematic coughs and upcoming events in cough science
CougH Science News July 2024 - latest in cough science. Insights on cough detection algorithms, pulmonary fibrosis, asthma diagnosis from cough sounds, and more. Plus, watch expert discussions and stay updated on upcoming events
Hyfe Cough Science News, June 2024. Latest research on cough in fibrotic ILD, high-dose inhaled corticosteroids for chronic cough, and family physicians’ approaches to managing chronic cough. Plus, insights from leading researchers and upcoming events
Cough Science News May 2024 - studies on cough monitoring for COVID-19 surveillance, the effectiveness of codeine for chronic cough, factors in refractory cough in IPF, and more. Plus, insights from researchers and upcoming events
Hyfe Cough Science News, March 2024 - insights on chronic cough management in the UK, common triggers in cough hypersensitivity, and a review of treatments for refractory cough. Plus, expert Q&A and upcoming cough science events.
Key Takeaway: For patients with fibrotic ILD, cough is an important and common symptom, and patient-reported cough severity is independently correlated with quality of life, disease progression and survival. This study of patients enrolled in the Canadian Registry for Pulmonary Fibrosis from 2015-2022 also found that there was no difference in worsening cough over time comparing those receiving and not receiving ILD-targeted therapy.
Why It Matters: The study suggests cough can be considered a prognostic biomarker in both idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic ILD. Given cough is now objectively measurable whilst patients go about their daily life, this understanding of the importance of cough could lead to a greater utility for cough monitoring in the management of ILD patients.
Key Takeaway: Of 50 patients with chronic cough and FeNO greater than or equal to 25 ppb, 68% responded to treatment with ICS (200mg of fluticasone furoate), with significant improvement in cough and FeNO levels. However, cough and FeNO levels were not significantly correlated with each other.
Why It Matters: This study supports the many cough guidelines that propose a short-term trial of ICS in patients with chronic cough and high FeNO levels. However the lack of correlation between cough and FeNO following treatment suggests the direct mechanistic link between the two is not fully understood.
Key Takeaways: Family care physicians in the US typically follow a patient-centric approach to treating chronic cough, and see it as a condition that can be managed mostly within the primary care setting. Survey respondents ranked highest “I try to assess for and to rule out most common causes of chronic cough through tests and trials of medications before I refer to a specialist.” and lowest “I refer all or most patients with chronic cough to a specialist for full evaluation.”
Why it matters: Despite family physicians expressing comfort with managing and treating chronic cough themselves and adherence to appropriate guidelines, only a minority agreed or strongly agreed that they were confident in their abilities to evaluate and treat chronic cough as a condition. This suggests a need for more education to validate strategies for managing chronic cough.
Exploring the Possibilities of Longitudinal Cough Data
Dr Grandjean Lapierre spoke to Hyfe about his trial called “Making Cough Count for Tuberculosis”, involving building a large open-source database of cough sounds, and longitudinal cough monitoring of patients after they seek care or are diagnosed with TB.
“The cough data can help in triaging patients and improving clinical management by identifying those who need more urgent care. The real value is that it’s highly accessible and virtually cost-neutral.”
Dr Simon Grandjean Lapierre
Assistant Professor at Université de Montréal
