Cough Science News
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
This month’s roundup explores placebo effects in RCC trials, the role of interoception in chronic cough, and the cost burden of persistent symptoms, plus insights from Dr. Nadia Giannetti.
New key cough science publications, Actigraph x Hyfe partnership and more
This year marked significant progress in cough monitoring, solidifying cough as a valuable biomarker in diverse therapeutic areas
New findings on refractory chronic cough (RCC), pulmonary tuberculosis, and pulmonary fibrosis. Plus latest white papers by Hyfe.
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News, August 2024 - Explore studies on cough variability, acute cough duration, and the cost burden of chronic cough. Plus, discover the world’s most comprehensive collection of cinematic coughs and upcoming events in cough science
CougH Science News July 2024 - latest in cough science. Insights on cough detection algorithms, pulmonary fibrosis, asthma diagnosis from cough sounds, and more. Plus, watch expert discussions and stay updated on upcoming events
Hyfe Cough Science News, June 2024. Latest research on cough in fibrotic ILD, high-dose inhaled corticosteroids for chronic cough, and family physicians’ approaches to managing chronic cough. Plus, insights from leading researchers and upcoming events
Cough Science News May 2024 - studies on cough monitoring for COVID-19 surveillance, the effectiveness of codeine for chronic cough, factors in refractory cough in IPF, and more. Plus, insights from researchers and upcoming events
Hyfe Cough Science News, March 2024 - insights on chronic cough management in the UK, common triggers in cough hypersensitivity, and a review of treatments for refractory cough. Plus, expert Q&A and upcoming cough science events.
Key Takeaway: 83% of respondents consider RCC/UCC to be a disease in itself - yet regarding management, one-third of respondents have never read a guideline, and 92% are seeking further education.
Why It Matters: The concept of RCC/UCC being a disease in its own right has only recently gained acceptance, but it is a view now widely held. Yet the approach to RCC/UCC, including diagnosis and pharmacotherapy, still varies significantly, within this UK-based study and between the UK and other countries where similar studies have been carried out.
Key Takeaway: In a qualitative study of the sensations and triggers experienced by patients with chronic cough, all patients reported hypertussia (e.g. smoke as trigger) and allotussia (e.g. talking as trigger), suggesting underlying neuropathology.
Why It Matters: Though the study featured just 10 pts, it improves our understanding of cough hypersensitivity from a patient’s perspective, which may help inform PROs. The identification of commonly experienced triggers and sensations may also inform the evolution of Behavioral Cough Suppression Therapy techniques.
Key Takeaways: This systematic literature review of 19 clinical trials of drugs for RCC/UCC found a high degree of heterogeneity in their design; from disease definitions, to inclusion/exclusion criteria, to outcomes measures. Whilst 13 assessed cough frequency (with the Leicester Cough Monitor being the most common tool), only 9 trials reported cough severity.
Why it matters: The study highlights the critical lack of approved therapies for UCC/ RCC and the significant variation in trial designs, populations, and outcomes. It underscores the need for more standardized and rigorous research in this area as well as the opportunity for novel approaches/ treatments.
Dr Reynolds spoke with us about her passion for Behavioral Cough Suppression Therapy (BCST), a non-pharmacologic treatment for patients with Refractory Chronic Cough. Her research aims to increase access to the impressive results achievable via BCST, by delivering BCST online.
“Most cough treatment research relies on self-reported questionnaires and while these provide valuable information, pairing these measures with cough frequency monitoring helps to tell a richer story about treatment response.[..] We hypothesize that patients who complete iBCST will see a meaningful reduction in [..] cough rates.”
Dr Jane Reynolds
Speech Language Pathologist, and Assistant Professor and co-director of the Voice Outcomes and Inquiries in Cough and Essentials of Swallowing (VOICES) lab at University of Montana in Missoula, Montana, USA.
